Oncology Clinical Trial Finder

Breast Cancer

Recruiting • Phase NA • Stage 0, I, II, III, IV • ER negative • Post-Menopausal • Interventional

The following is imported from ClinicalTrials.gov:

3-D Super Resolution Ultrasound Microvascular Imaging

This is a 3-arm single center study of 45 patients. These cohorts will include 15 breast patients scheduled to undergo a biopsy, and 15 thyroid patients scheduled to undergo fine needle aspiration, biopsy, or thyroidectomy that consent to undergo an acoustic angiography in conjunction with b-mode ultrasound prior to their scheduled biopsy. Prior to imaging clinical patients, the third arm will include 15 healthy volunteers that will be imaged to optimize imaging parameters.

Increasing the sensitivity and specificity of diagnostic imaging in patients at high risk for breast or thyroid cancer could provide substantial clinical benefit by improving diagnosis, preventing over-treatment, and reducing healthcare costs. Acoustic angiography is a new type of contrast enhanced ultrasound imaging which is specifically sensitive to microvascular structure and density. It evaluates tumor micro-vasculature and may provide a powerful prognostic tool for the diagnosis of breast cancer, and eventually for treatment evaluation.

Breast Cancer

Study Design

Study type:


Estimated enrollment:

45 participant

Actual study start date:

May 26, 2022

Eligibility Criteria

Ages eligible for study:

18 - 999

Sexes eligible for study:


Arms and Intervention

  • Definity

  • Acoustic Angiography

Trial Information at Site

Last Updated:

Trial Information

ClinicalTrial.gov ID:


Estimated Enrollment:


Last Updated:


Site Contact

Carly Sronce



Univeristy of North Carolina Chapel Hill

Chapel Hill, North Carolina, United States, 27599

Trial Contact

Carly Sronce



Desma Jones, CCRC



Principal Investigator

Yueh Lee, MD, PhD

Trial Sponsor

UNC Lineberger Comprehensive Cancer Center

Study Location (1)

Univeristy of North Carolina Chapel Hill

Chapel Hill, North Carolina, United States


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